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Fused Heterocyclic compounds.

 

Organoboronic acids/esters.

 

Unnatural amino acids.

 

Fluorination and chlorination (from laboratory scale to manufacturing scale).

 

Peptide synthesis and modifications.

 

Precious metal catalysts or precursors custom manufacturing, process optimization and scale up, and catalysts recycling.

 

Catalyst screening service (at laboratory scale).

 

High temperature, high pressure reactions – carbonylation, catalytic reduction, asymmetric hydrogenation, etc (from laboratory scale to manufacturing scale).

 

Transition metal mediated chemical reactions.

 

Synthesis of reference compounds, impurities, metabolites and their stable isotope labeled analogs.

 

Multistep asymmetric synthesis.

 

Chiral separation via diastereomeric salt formation.

 

Chiral HPLC method development.